Thank you for being part of the SepTiC team!
For SepTiC, our target is to recruit 3758 participants in 60 sites throughout the UK.
The SepTiC trial is now open to recruitment.
The trial is currently open at 36 sites and has recruited over 580 patients.
We are looking for more sites to join the trial and are currently accepting expressions of interest from participating sites.
SepTiC Monthly Q&A Series:
Tuesday 3rd March 2026 11:00-12:00
Monthly Q&A session with the Chief Investigator and research team
Wednesday 15th April 2026 14:00-15:00
Monthly Q&A session with the Chief Investigator and research team
Monday 18th May 11:00-12:00
Q&A with the Imperial Critical Care Research Team
See recordings of our previous webinars under the ‘Training Videos’ Tab
Join Zoom Meeting for the SepTiC Monthly Q&A Sessions:
https://imperial-ac-uk.zoom.us/j/93817767036?pwd=SzVFV01uZE8zaUp5dzFmZUdTckhkdz09
Meeting ID: 938 1776 7036
Passcode: 1LmN^L
All the information you need is right here!
SepTiC API Forum:
The SepTiC Trial is registered with the Associate Principal Investigator (PI) Scheme – click here to apply to be an Associate PI
SepTiC API Forum Meeting 11.02.2025
SepTiC Webinar:
SepTiC Webinar Series Schedule
Patient Information Sheet full V4.0 15.12.2025
Patient Information Sheet Summary V3.0 15.12.25
Personal legal summary (Relatives) V3.0 17DEC24
Professional legal summary V3.0 17DEC24
Telephone Agreement V2.0 14MAR25
Retrospective PIS full V3.0 15.12.25
Manuals:
Templates:
Pharmacy IMP Accountability Log
Initial Kit Allocation Email Template
SepTiC Fluid Trial Manual v1.0 10.11.2023
SepTiC Fluid Intervention 1 Page Summary
SepTiC eCRF Completion Guidelines v3.0 26.11.2025
SepTiC Sample Manual V3.0 02.02.2026
SepTiC Sample Shipping Form v2.0 02.02.2026
SepTiC Note To File Template v2.0 24.06.2024
SepTiC Randomisation Guide v3.0 01.10.2024
SepTiC Randomisation Crib sheet 1_ v1.0 11.06.2024
SepTiC Randomisation Crib Sheet_2 v3.0 20.05.2025
SepTiC Randomisation and Troubleshooting Guide v1.0 23.04.2025
Patient Information Sheet full
Patient Information Sheet full V3.0 17DEC24
Patient Information Sheet Summary
Patient Information Sheet Summary V2.0 17DEC24
Personal legal summary ( Relatives)
Retrospective PIS full V2.0 17DEC24
Retrospective PIS summary V2.0 17DEC24
Sealed Envelope (Unblinded Pharmacist) Training Slides v1.0 14.03.24
Sealed Envelope (Unblinded Pharmacist) Training Log v1.0 14.03.24
Randomisation on OpenClinica Video
Multi factor authentication on OpenClinica Video
Webinars:
SepTiC Virtual Webinar 24.11.23
SepTiC Virtual Q&A Webinar 07.02.24
SepTiC Virtual Q&A Webinar 11.03.24
SepTiC Virtual Q&A Webinar 22.08.24 – Fluid Intervention
SepTiC Virtual Q&A Webinar 18.09.24 – GM-CSF Intervention
SepTiC Virtual Q&A Webinar 08.10.24 – Eligibility
SepTiC Virtual Q&A Webinar 11.11.24 – Data entry
SepTiC Virtual Q&A Webinar 04.12.24
SepTiC Virtual Q&A Webinar 22.01.25
SepTiC Virtual Webinar 11.03.25
SepTiC Virtual Q&A Webinar 12.05.25 – Fluid Intervention
SepTiC Virtual Q&A Webinar 17.06.25
SepTiC Virtual Q&A Webinar 11.11.25 – GM-CSF Intervention
SepTiC Virtual Q&A Webinar 11.12.25
SepTiC Virtual Webinar 05.02.26 – PCR/ PCT intervention with Prof Paul Dark
Follow us on Twitter at @septictrial
Download Past Newsletters
SepTiC September 2024 Newsletter
SepTiC October 2024 Newsletter
SepTiC November 2024 Newsletter
SepTiC December 2024 Newsletter
SepTiC January 2025 Newsletter
SepTiC February 2025 Newsletter
SepTiC September 2025 Newsletter
SepTiC October 2025 Newsletter
SepTiC November 2025 Newsletter
SepTiC December 2025 Newsletter
SepTiC January 2026 Newsletter
SepTiC February 2026 Newsletter
List of sites
St Mary’s Hospital, London
Charing Cross Hospital, London
Hammersmith Hospital, London
Queen Alexandra Hospital, Portsmouth
Kings Mill Hospital, Nottinghamshire
Kettering General Hospital, Northamptonshire
Bristol Royal Infirmary, Bristol
James Cook University Hospital, Middlesbrough
St George’s Hospital, London
Russells Hall Hospital, Dudley
Sunderland Royal Hospital, Sunderland
Watford General Hospital, Watford
Derriford Hospital, Plymouth
Kings College London, London
Scunthorpe General Hospital, North Lincolnshire
Royal Stoke Hospital, Stoke-on-Trent
Royal Victoria Hospital, Belfast
Belfast City Hospital, Belfast
Darent Valley Hospital, Dartford
Royal Glamorgan Hospital, South Wales
Southampton General Hospital, Southampton
Musgrove Park Hospital, Somerset
Countess of Chester Hospital, Cheshire
Salford Royal Hospital, Salford
Hull Royal Infirmary, Hull
Royal Victoria Infirmary, Newcastle
Freeman Hospital, Newcastle
Southend University Hospital, Westcliff-On-Sea
Queens Medical Centre, Nottingham
Southmead Hospital, Bristol
Warrington Hospital, Warrington
Huddersfield Royal Infirmary, Halifax
Calderdale Royal Hospital, Halifax
John Radcliffe Hospital, Oxford
Cleveland Clinic, London
Stoke Mandeville Hospital, Aylesbury
For sites: sign up to receive your SepTiC newsletter!
@CHFTResearch
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